PolyTherics Ltd - News on 07 August 2007

2008
PolyTherics and Alligator Bioscience announces strategic collaboration for optimisation of next generation biopharmaceuticals
Secretary of State John Denham visits PolyTherics
Novel Approach to Drug Insolubility strengthens PolyTherics patent estate
PolyTherics expands Collaboration with Biocompatibles
PolyTherics-Celtic Pharma Collaboration Agreement to explore technologies for improved drug performance
New Consortium announces Significant Grant Funding of Anaemia product programme

2007
Innovative Drug Production Project secures funding from Technology Strategy Board
Imperial Innovations Annual Report - PolyTherics Limited
PolyTherics highlighted by UK Trade & Investment
Antony Godwin from PolyTherics ties the knot
PolyTherics and BioVectra dcl sign Manufacturing and Representation Deal
Innovative Biopharmaceutical Company, PolyTherics, raises over £2 million
TheraPEG ™ technology ideal for drugs for developing countries

2006
TheraPEG ™ technology wins Research Breakthrough Award
NHS at Hammersmith Hospital applauds new PEGylated IFN
PolyTherics nominated Regional Finalist in UK Biotechnology Entrepreneur Awards 2006
PolyTherics PEGylation technology published in Nature
Debbie Allen and Geeta Gupta joins PolyTherics

2005
PolyTherics and Shantha sign biotech deal
BangaloreBio begins
British High Commissioner addresses Indian biotech companies

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PolyTherics and BioVectra dcl sign Manufacturing and Representation Deal

PolyTherics, a biopharmaceutical spin-out company from Imperial College London and the London School of Pharmacy, today announced that it has signed a manufacturing and bilateral representation agreement with BioVectra dcl, a Canadian biopharmaceutical company that supplies specialty chemicals and contract manufacturing services to the pharmaceutical and biotechnology industry.

The agreement, which follows hard on the heels of PolyTherics' recent successful fundraising of over £2 million, will see BioVectra manufacturing high quality cGMP MPEG reagents to support client's clinical development of PolyTherics' novel PEGylation technology. BioVectra will also market the PEGylation technology to its client base in North America.

PolyTherics has developed patent-protected proprietary technologies and expertise in the modification of drugs to improve their performance. The Company's innovative PEGylation technology, known as TheraPEG ™, can extend the half-life of novel and existing protein drugs. The TheraPEG ™ approach produces an improvement in biological activity and a higher yield than the existing PEGylation technologies. This means that drugs, such as Interferon, stay active in the body for longer, enabling longer periods between doses. Patients can therefore be treated less often, with fewer side-effects and at lower cost.

The market for traditional PEGylation has expanded considerably and PolyTherics' TheraPEG ™ technology is positioned both to address existing markets and open new markets, particularly in the antibody field. PolyTherics already has revenue-generating development contracts in place with several companies and is in discussion with a number of other parties.

Dr Keith Powell, CEO of PolyTherics, said: "We are delighted to have signed this agreement with BioVectra, who offer access to specialist custom polymer chemistry capabilities, a patented MPEG purification process and scaled manufacturing systems - the key components that are needed to support clients of our TheraPEG ™ technology.

"We are currently in discussion with a number of biogeneric and pharmaceutical companies in Europe and the USA and there is significant interest in downstream applications for our TheraPEG ™ technology. This agreement with BioVectra means that we can work with a highly competent manufacturer who will supply the highest quality MPEGs to meet our clients' needs and comply with FDA standards. So we now have the tools to take our TheraPEG ™ technology from the laboratory into the feasibility testing and manufacturing stages."

Stephen Ball, Business Development Representative for BioVectra, said: "We are pleased to be working with PolyTherics to support the development of their innovative and important site specific TheraPEG ™ technology. We look forward to deploying our capabilities in the manufacturing of high quality cGMP MPEG reagents to assist PolyTherics' clients through clinical development of therapeutic proteins into post approval commercialization."

Dale Zajicek, Chief Operating Officer of BioVectra, said: "We remain committed to supporting our PEGs business initiatives with technology that creates true value for our customers and their patients. The PolyTherics agreement is a clear example of this commitment."

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7 August 2007

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