PolyTherics Ltd - News on 26 February 2008

2008
PolyTherics and Alligator Bioscience announces strategic collaboration for optimisation of next generation biopharmaceuticals
Secretary of State John Denham visits PolyTherics
Novel Approach to Drug Insolubility strengthens PolyTherics patent estate
PolyTherics expands Collaboration with Biocompatibles
PolyTherics-Celtic Pharma Collaboration Agreement to explore technologies for improved drug performance
New Consortium announces Significant Grant Funding of Anaemia product programme

2007
Innovative Drug Production Project secures funding from Technology Strategy Board
Imperial Innovations Annual Report - PolyTherics Limited
PolyTherics highlighted by UK Trade & Investment
Antony Godwin from PolyTherics ties the knot
PolyTherics and BioVectra dcl sign Manufacturing and Representation Deal
Innovative Biopharmaceutical Company, PolyTherics, raises over £2 million
TheraPEG ™ technology ideal for drugs for developing countries

2006
TheraPEG ™ technology wins Research Breakthrough Award
NHS at Hammersmith Hospital applauds new PEGylated IFN
PolyTherics nominated Regional Finalist in UK Biotechnology Entrepreneur Awards 2006
PolyTherics PEGylation technology published in Nature
Debbie Allen and Geeta Gupta joins PolyTherics

2005
PolyTherics and Shantha sign biotech deal
BangaloreBio begins
British High Commissioner addresses Indian biotech companies

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PolyTherics and Celtic Pharma sign Collaboration Agreement to explore technologies for improved drug performance

PolyTherics Limited ("PolyTherics"), a biopharmaceutical spin-out company from Imperial College London and the London School of Pharmacy, and Celtic Pharma Development Services Bermuda Ltd ("Celtic Pharma"), a subsidiary of Celtic Pharmaceutical Holdings LP, a global private equity investment fund focused on the biopharma industry, today announced that they have entered into a broad research collaboration agreement. Under the terms of the agreement, PolyTherics' proprietary drug modification technologies will be used to enhance certain of the innovative pharmaceutical products being developed by Celtic Pharma.

The parties plan jointly to develop and validate modifications of drugs submitted to the collaboration by Celtic Pharma, in order to improve their performance and assess their future development potential.

PolyTherics has substantial expertise in the targeted and selective modification of compounds for therapeutic and diagnostic application. Through the application of a platform of polymer-based technologies, it is developing compounds as drug candidates in both existing and emerging markets. With the growing commercial impact of biopharmaceutical products, and particularly next generation antibody fragments, PolyTherics is strongly positioned to address these opportunities. PolyTherics has revenue-generating research and development contracts in place with several companies and is in discussion with a number of others.

Dr Keith Powell, Chief Executive Officer of PolyTherics, said: "We view collaboration through partnership as fundamental to exemplifying the development potential of our proprietary technologies and fulfilling our strategy. The opportunity to collaborate with a high calibre, product-focused company such as Celtic Pharma is a significant milestone in the development of PolyTherics, and we are delighted to be working with Celtic Pharma on several of the products in their portfolio. We believe that our work together will show that PolyTherics' proprietary technologies can be used to improve pharmaceutical products to increase their commercial value."

Celtic Pharma currently has a portfolio of nine novel pharmaceutical products in clinical development across a range of therapeutic areas. Each product is being developed to address important unmet medical needs, and Celtic Pharma aims to move these products rapidly and effectively through clinical development to regulatory approval.

Dr Bill Henry, Managing Director - Global Head of CMC at Celtic Pharma, said: "We are excited about accessing the technology capability of PolyTherics through collaboration and exploring its potential impact on our product pipeline."

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26 February 2008

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